Polynucleotide · Skin Regeneration

Rejuran

Repair the Dermis From Within

Polynucleotide (PN/PDRN) salmon-DNA fragments that prompt the skin to rebuild itself — improving density, fine lines, and resilience rather than simply adding volume.

from ₩220,000 Final price confirmed at consultation Healer · HB · White Course Recommended

Product chosen by skin goal

Price confirmed in person

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Why Patients Trust Tune

A physician plans and performs every treatment.

No brokers. No commissioned referrals. Every booking begins with a doctor on the Tune medical board — the same people accountable for your result.

A Named Board

American Board of Aesthetic Medicine · Clinical Professors of Plastic Surgery (Yonsei) and Medicine (Chosun) · Director, Korean Stem Cell Society.

Where You'll Be

Apgujeong, Seoul — between Apgujeong Rodeo and Sinsa stations, in Korea's most-searched aesthetic district.

An Honest Plan

Your plan is confirmed in person before anything begins. Outcomes and suitability vary by individual — we tell you when a treatment isn't right for you.

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Best For

Skin density & fine lines

Downtime

Mild marks, ~24h

Type

Regenerative injection

The Treatment

What Is Rejuran?

Rejuran is a regenerative injectable made from purified polynucleotides — DNA fragments derived from salmon — that signal the skin to repair and rebuild.

Rather than filling a line, the polynucleotides support fibroblast activity and the skin's own collagen and elastin, gradually improving density, smoothness, hydration, and tone. It is a skin-quality treatment, not a volumizer.

Several formulations exist — Healer for overall skin repair, HB for hydration with hyaluronic acid, and Rejuran White for brightening support. The physician selects the product and depth that match your skin.

The Range

Choosing the Right Rejuran

Type	Focus	Often Used For
Healer	Overall repair	Density, texture, resilience
HB	Repair + hydration	Glow & fine lines
Rejuran White	Brightening support	Tone & dull skin

Final product selection is confirmed by the physician.

Expected Effects

What Rejuran Targets

Skin Density

Fine Lines

Elasticity

Glow & Tone

Individual results vary.

Treatment Logistics

Time in Clinic

About 20–30 min

Comfort

Numbing applied
brief pinpricks

Recovery

Small bumps/marks
settle within ~24h

Plan

Course of 3–4 sessions

Spaced 2–4 weeks apart

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Tune Clinic

Recommended For

1Those with thin, tired, or dehydrated skin that has lost bounce.
2Those bothered by fine lines, crepey texture, or early under-eye crinkling.
3Those who want to improve skin quality rather than add volume.
4Those preparing skin before or alongside lifting and volume treatments.
5Those seeking a natural, gradual improvement built on their own collagen.

Precaution

After-Care Notes

Small bumps, redness, or mild bruising at injection points usually settle within about a day.
Avoid heavy makeup, saunas, and intense exercise for the first day after treatment.
A course of sessions gives the most noticeable, lasting change; results build over weeks.
Tell the physician about any salmon/fish allergy or active skin infection before treatment.
If pregnant or breastfeeding, it is best to postpone this treatment.

Physician's FAQ

How is Rejuran different from filler or skin boosters?

Filler adds volume and most hydration boosters mainly draw water into the skin. Rejuran's polynucleotides instead encourage the skin to repair and rebuild its own structure, improving density and resilience over time. The physician may combine approaches when appropriate. Individual results vary.

How many sessions will I need?

A typical starting course is three to four sessions spaced two to four weeks apart, with periodic maintenance afterward. The exact plan depends on your skin condition and goals and is confirmed at consultation.

Is there downtime for travelers?

Tiny bumps and mild redness or bruising can appear at the injection points and usually settle within about a day, so plan around 24 hours before major events. Let us know your travel dates and we will sequence accordingly.